Bioavailability of a drug given by the IV route is which percentage?

Enhance your readiness for the MEDNAX Neonatal Nurse Practitioner Exam. Utilize flashcards, multiple-choice questions, and detailed explanations. Equip yourself for success!

Multiple Choice

Bioavailability of a drug given by the IV route is which percentage?

Explanation:
Bioavailability is the fraction of an administered dose that reaches the systemic circulation in active form. When a drug is given intravenously, it is delivered directly into the bloodstream, bypassing absorption barriers such as the gut lining and first-pass metabolism. Because there is no loss due to absorption, the entire dose reaches systemic circulation unchanged (assuming no immediate degradation or loss during administration). Hence the bioavailability is 100%. Values like 80% or 90% would imply incomplete absorption, which does not apply to IV administration, and a value over 100% isn’t physiologically possible.

Bioavailability is the fraction of an administered dose that reaches the systemic circulation in active form. When a drug is given intravenously, it is delivered directly into the bloodstream, bypassing absorption barriers such as the gut lining and first-pass metabolism. Because there is no loss due to absorption, the entire dose reaches systemic circulation unchanged (assuming no immediate degradation or loss during administration). Hence the bioavailability is 100%. Values like 80% or 90% would imply incomplete absorption, which does not apply to IV administration, and a value over 100% isn’t physiologically possible.

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