In a full-term female infant, clitoral enlargement is considered abnormal when the clitoral width exceeds which value?

• A. 4 cm
• B. 6 cm
• C. 2 cm
• D. 8 cm

Answer: (B)

Clitoromegaly in a newborn is a sign of possible androgen exposure in utero and prompts evaluation for disorders of sexual development, such as congenital adrenal hyperplasia. In a full-term female infant, an abnormal clitoral width is considered when it exceeds six centimeters. This threshold helps distinguish normal variation from pathologic enlargement that requires further workup, including endocrine testing (like 17-hydroxyprogesterone) and a thorough genital exam for virilization signs. If the measurement is smaller than this cut-off, it does not rule out other issues, but it is less concerning from a virilization standpoint.