In Apert syndrome, which limb feature is typically present?

• A. Unilateral syndactyly
• B. No limb anomalies
• C. Extra phalanges
• D. Symmetric syndactyly of the hands and feet

Answer: (D)

Apert syndrome presents with limb features that are characteristically bilateral and symmetric. The digits of both hands and both feet fuse together early in development, giving mitten-like hands and often fused toes. This symmetric syndactyly arises from the underlying mutation affecting early limb morphogenesis, so you see the same pattern on both sides rather than unilateral involvement or isolated anomalies. Extra digits or lack of limb anomalies aren’t typical for this syndrome, making symmetric syndactyly of the hands and feet the hallmark feature.