Postaxial polydactyly in African American infants is typically.

• A. Associated with chromosomal abnormalities
• B. An isolated malformation
• C. Associated with a multiple malformation syndrome
• D. None of the above

Answer: (B)

Postaxial polydactyly on the little-finger side is most often an isolated finding in African American infants. This means it typically occurs without other congenital anomalies or involvement of multiple organ systems. Because of that, it is not usually a marker for chromosomal abnormalities or for a broader multiple malformation syndrome. In a child without additional dysmorphic features or health issues, the extra digit can be managed with observation or elective surgical correction if desired. While polydactyly can be syndromic in some cases, the common scenario in this population is a standalone malformation, which is why an isolated malformation best fits.