What is the normal glucose requirement for preterm infants?

• A. 3-5 mg/kg/min
• B. 8-10 mg/kg/min
• C. 10-12 mg/kg/min
• D. 6-8 mg/kg/min

Answer: (D)

Preterm infants rely heavily on glucose for energy because their glycogen stores are limited and their glucose metabolism is immature. To prevent hypoglycemia and support growth, a maintenance glucose infusion rate of about 6 to 8 mg/kg per minute is commonly used. This range provides sufficient energy without pushing blood glucose too high. Rates lower than this increase the risk of hypoglycemia, while higher rates raise the risk of hyperglycemia and its complications. In practice, the rate is individualized and adjusted based on frequent glucose monitoring to keep glucose within a safe neonatal range.