Which condition is Potter sequence typically associated with?

• A. Meckel's Syndrome
• B. Potter Sequence
• C. Turner’s Syndrome
• D. Down Syndrome

Answer: (B)

Potter sequence is produced when there is very little amniotic fluid (oligohydramnios) during fetal life. That lack of fluid is usually caused by problems with the fetal kidneys, most classically bilateral renal agenesis, though other severe urinary tract abnormalities can do it as well. The reduced amniotic fluid means less cushioning and space for the developing fetus, leading to the characteristic Potter facies, limb deformities, and, critically, pulmonary hypoplasia due to insufficient fluid for normal lung development.

Among the given options, conditions that cause severe renal problems and oligohydramnios are the ones that fit this sequence. Turner’s and Down syndromes are not typically associated with oligohydramnios or Potter sequence as a primary driver. Meckel-Gruber (Meckel’s) syndrome, on the other hand, involves renal dysplasia or anomalies that can lead to oligohydramnios and the resulting Potter-type findings, making it the best association among the choices.